Fragment 176-191 & Mod GRF 1-29 & Ipamorelin Blend (12mg)

Fragment 176-191 & Mod GRF 1-29 & Ipamorelin Peptide Blend

Studies have suggested that a maximal output of endogenous growth hormone (GH) from the anterior pituitary gland might be attained through a combination of growth hormone-releasing hormone (GHRH) analog and agonist of growth hormone secretagogue receptor (GHSR).[1] The combination of Ipamorelin with Modified GRF is one of the various combinations researchers have studied in an effort to achieve maximal growth hormone production. Interestingly, more specific results appear to be achieved beyond the increase in GH synthesis by refining the choice of GHRH and GHSR evaluated in a particular study. Modified GRF, which researchers have suggested may be a potent GHRH analog, may have impacts beyond growth hormone release. It has been speculated to impact intestinal inflammation, tissue repair, and cardiac function in addition to researchers’ suppositions on its impact on growth hormone release. Ipamorelin, classified as a growth hormone secretagogue, appears to interact with the GHSRs, also known as ghrelin receptors, and may have the potential to impact bone growth. Activating the ghrelin receptors may affect appetite, to increase food consumption and total weight gain. Depending on the desired outcome of the particular study, namely the addition or reduction of weight, this specific receptor activity may be mitigated by adding lipolytic molecules, which may help minimize the possibility of fat increase. Fragment 176-191 is often combined with Ipamorelin and other research peptides. The peptide known as Fragment 176-191, also referred to as hGH Fragment 176-191, Frag 176-191, tyr-hGH 177-191, or AOD-9604, is hypothesized to specifically target the fat-reduction pathways of growth hormone. This peptide consists of a sequence of 16 amino acids derived from the terminal portion of the growth hormone molecule, identified by researchers as the “lipolytic fragment” due to its potential fat-burning capabilities. The term ‘lipolytic’ describes the fragment’s capacity to promote fat breakdown. To enhance the peptide’s stability, the initial amino acid in the hGH Fragment 176-191 sequence is substituted with tyrosine, leading to its alternate designation as Fragment tyr-hGH 177-191.[2][3]

Fragment 176-191 Specifications

Molecular Formula: C78H125N23O23S2

Molecular Weight: 1817.1 g/mol

Sequence: Tyr-Leu-Arg-Ile-Val-Gin-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

Mod GRF 1-29 Specifications

Molecular Formula: C152H252N44O42

Molecular Weight: 3367.95 g/mol

Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

Ipamorelin Specifications

Molecular Formula: C38H49N9O5

Molecular Weight: 711.85 g/mol

Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2